Product Overview
Bisantrene HCl | T4047L | TargetMol Chemicals
CAS: 71439-68-4
Smiles: Cl.Cl.C1CN=C(N\N=C/c2c3ccccc3c(\C=N/NC3=NCCN3)c3ccccc23)N1
Formula: C22H24Cl2N8
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Bisantrene (CL-216942; NSC 337766) is a topoisomerase II poison and DNA intercalator. It can be used as a Rac1 inhibitor or model compound to study P-glycoprotein-mediated multi-drug resistance (MDR1). Bisantrene inserts and disrupts the configuration of DNA, leading to DNA single-strand breaks, DNA-protein cross-links, and DNA replication inhibition.
Molecular Weight: 471, 39
