Product Overview
BIX02188 | T6324 | TargetMol Chemicals
CAS: 1094614-84-2
Smiles: CN(C)Cc1cccc(N\C(c2ccccc2)=C2/C(=O)Nc3cc(ccc23)C(N)=O)c1
Formula: C25H24N4O2
Pathway: MAPK|||Stem Cells
Target: ERK|||MEK|||TGF-beta/Smad
Receptor: N/A
Bioactivity: BIX02188 is a specific MEK5 inhibitor (IC50: 4.3 nM), also inhibits ERK5 catalytic activity (IC50: 810 nM), and does not inhibit closely related kinases MEK1/2, JNK2, and ERK2.
Molecular Weight: 412, 48