Product Overview
BMS-1166 hydrochloride | T14670 | TargetMol Chemicals
CAS: 2113650-05-6
Smiles: Cl.Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CN3C[C@H](O)C[C@@H]3C(O)=O)cc2Cl)cccc1-c1ccc2OCCOc2c1
Formula: C36H34Cl2N2O7
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM). BMS-1166 hydrochloride is an inhibitor of PD-1/PD-L1 interaction (IC50: 1.4 nM). BMS-1166 rivalries the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
Molecular Weight: 677, 58
