Product Overview
BMS-8 | T26859 | TargetMol Chemicals
CAS: 1675201-90-7
Smiles: Cc1c(COc2ccc(CN3CCCCC3C(O)=O)cc2Br)cccc1-c1ccccc1
Formula: C27H28BrNO3
Pathway: Apoptosis|||Cell Cycle/Checkpoint|||Immunology/Inflammation
Target: PD-1/PD-L1
Receptor: N/A
Bioactivity: BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.
Molecular Weight: 494, 429
