Product Overview
Brefeldin A | T6062 | TargetMol Chemicals
CAS: 20350-15-6
Smiles: [H][C@@]12C[C@H](O)C[C@@]1([H])[C@H](O)\C=C\C(=O)O[C@@H](C)CCC\C=C\2
Formula: C16H24O4
Pathway: Autophagy|||DNA Damage/DNA Repair|||Membrane transporter/Ion channel|||Microbiology/Virology
Target: ATPase|||Mitophagy|||Antibiotic|||Autophagy|||HSV|||CRISPR/Cas9
Receptor: N/A
Bioactivity: Brefeldin A, a Penicillium brefeldianum metabolite, which is a macrocyclic lactone exhibiting a wide range of antibiotic activity. It is also an ATPase inhibitor for protein transport in HCT 116 cells(IC50=0.2 μM), inducing Y cell differentiation and apoptosis.
Molecular Weight: 280, 364