Product Overview
Brepocitinib | TQ0010 | TargetMol Chemicals
CAS: 1883299-62-4
Smiles: Cn1cc(Nc2nccc(n2)N2CC3CCC(C2)N3C(=O)[C@@H]2CC2(F)F)cn1
Formula: C18H21F2N7O
Pathway: Angiogenesis|||Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells|||Tyrosine Kinase/Adaptors
Target: Tyrosine Kinases|||JAK
Receptor: N/A
Bioactivity: Brepocitinib is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits JAK2/3 (IC50s: 77 nM/6.49 μM).
Molecular Weight: 389, 411