Product Overview
Britannilactone diacetate | TN2511 | TargetMol Chemicals
CAS: 1286694-67-4
Smiles: C[C@@H](CCCOC(C)=O)C1=C(C)C[C@H]2OC(=O)C(=C)[C@H]2[C@@H]1OC(C)=O
Formula: C19H26O6
Pathway: Angiogenesis|||Apoptosis|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Immunology/Inflammation|||JAK/STAT signaling|||MAPK|||Proteases/Proteasome|||Stem Cells
Target: IL Receptor|||PARP|||ROS|||MAPK|||Caspase|||JAK|||JNK|||STAT
Receptor: N/A
Bioactivity: 1, 6-O, O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airway disease as a lead compound. OODBL has anti-asthmatic activity, it reduces leukotriene C4 production and degranulation through the suppression of cytosolic phospholipase A2 phosphorylation and phospholipase Cγ-mediated Ca2+ influx in IgE/antigen-stimulated BMMCs. OODBL also exhibits potent antitumor activity against several human cancer cell lines.
Molecular Weight: 350, 4
