Product Overview
Bryostatin 1 | T14831 | TargetMol Chemicals
CAS: 83314-01-6
Smiles: [H][C@]12C[C@H](OC(C)=O)C(C)(C)[C@](O)(C[C@]3([H])C\C(C[C@@]([H])(O3)\C=C/C(C)(C)[C@]3(O)O[C@@]([H])(C\C(=C/C(=O)OC)[C@@H]3OC(=O)\C=C\C=C\CCC)C[C@@]([H])(OC(=O)C[C@H](O)C1)[C@@H](C)O)=C\C(=O)OC)O2
Formula: C47H68O17
Pathway: Chromatin/Epigenetic|||Cytoskeletal Signaling|||Microbiology/Virology|||Proteases/Proteasome
Target: HIV Protease|||PKC
Receptor: N/A
Bioactivity: Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a CNS)permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein (Kis: 8.07 nM and 0.45 nM).
Molecular Weight: 905, 044
