Product Overview
BTYNB | T9033 | TargetMol Chemicals
CAS: 304456-62-0
Smiles: C1=CC=C(C(=C1)C(=O)N)N=CC2=CC=C(S2)Br
Formula: C12H9BrN2OS
Pathway: Cell Cycle/Checkpoint|||NF-Κb|||Others
Target: Others|||c-Myc|||NF-κB
Receptor: N/A
Bioactivity: MDK6620 is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 μM for IMP1 binding to c-Myc mRNA). MDK6620 downregulates β-TrCP1 mRNA and reduces activation of nuclear transcriptional factors-kappa B (NF-κB). It disrupts this enhancer function by impairing IGF2 mRNA-binding protein 1 (IGF2BP1)-RNA association
Molecular Weight: 309, 18