Carbamazepine 10, 11-epoxide | T37149

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TMC-T37149
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Product Overview

Carbamazepine 10, 11-epoxide | T37149 | TargetMol Chemicals

CAS: 36507-30-9

Smiles: NC(=O)N1c2ccccc2C2OC2c2ccccc12

Formula: C15H12N2O2

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: Carbamazepine 10, 11-epoxide is an active metabolite of the anticonvulsant carbamazepine[1][2].It is formed from carbamazepine by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes prepared from HepG2 cells expressing CYP3A4 or CYP2C8, respectively[1].Carbamazepine 10, 11-epoxide has anticonvulsant activity against maximal electroshock-induced seizures in mice.2It has been found in wastewater effluent[3].

Molecular Weight: 252, 273

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