Product Overview
CDK12-IN-E9 | T14915 | TargetMol Chemicals
CAS: 2020052-55-3
Smiles: CCc1cnn2c(Nc3cccc(NC(=O)C=C)c3)cc(nc12)N1CCCC[C@H]1CCO
Formula: C24H30N6O2
Pathway: Cell Cycle/Checkpoint
Target: CDK
Receptor: N/A
Bioactivity: CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and non-covalent CDK9 inhibitor while avoiding ABC transporter-mediated efflux. It has a weak binding ability to CDK7/CyclinH complex (IC50> 1 μM).
Molecular Weight: 434, 544
