Product Overview
Cenupatide | TP2338 | TargetMol Chemicals
CAS: 1006388-38-0
Smiles: OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NC(C)(C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@](C)(Cc1ccccc1)C(N)=O
Formula: C32H49F6N11O9
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Cenupatide is a urokinase plasminogen activator receptor (uPAR) inhibitor. Cenupatide inhibits uPAR binding to the formyl peptide receptors (FPRs) can improve kidney lesions in a rat model of STZ-induced diabetes. Cenupatide reverted STZ-induced up-regulation of uPA levels and activity, while uPAR on podocytes and (s)uPAR were unaffected. In glomeruli, Cenupatide inhibited FPR2 expression.
Molecular Weight: 845, 802
