Product Overview
CH-0793076 | T14945 | TargetMol Chemicals
CAS: 534605-78-2
Smiles: CCCCCn1cnc2cccc3nc-4c(Cn5c-4cc4c(COC(=O)[C@]4(O)CC)c5=O)c1c23
Formula: C26H26N4O4
Pathway: DNA Damage/DNA Repair
Target: Topoisomerase
Receptor: N/A
Bioactivity: CH-0793076, a hexacyclic camptothecin analog, is an active drug and major metabolite of TP300. CH-0793076 is efficacious against cells expressing BCRP (breast cancer resistance protein). CH-0793076 inhibits DNA topoisomerase I (IC50: 2.3 μM).
Molecular Weight: 458, 518
