Product Overview
CHIR 98024 | T3074 | TargetMol Chemicals
CAS: 556813-39-9
Smiles: Nc1nc(NCCNc2ncc(-c3ncc[nH]3)c(n2)-c2ccc(Cl)cc2Cl)ccc1[N+]([O-])=O
Formula: C20H17Cl2N9O2
Pathway: MAPK|||PI3K/Akt/mTOR signaling|||Stem Cells
Target: GSK-3|||S6 Kinase
Receptor: N/A
Bioactivity: CHIR 98024 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
Molecular Weight: 486, 32