Product Overview
CID44216842 | T8930 | TargetMol Chemicals
CAS: 1222513-26-9
Smiles: COc1cccc(c1)C1=NN(C(C1)c1ccc(Br)cc1)c1ccc(cc1)S(N)(=O)=O
Formula: C22H20BrN3O3S
Pathway: Cell Cycle/Checkpoint|||GPCR/G Protein|||MAPK
Target: CDK|||Ras
Receptor: N/A
Bioactivity: CID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe.
Molecular Weight: 486, 38