Ciliobrevin D | T14965

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TMC-T14965
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Product Overview

Ciliobrevin D | T14965 | TargetMol Chemicals

CAS: 1370554-01-0

Smiles: Clc1ccc(C(=O)C(\C#N)=C2/NC(=O)c3ccc(Cl)cc3N2)c(Cl)c1

Formula: C17H8Cl3N3O2

Pathway: GPCR/G Protein|||Membrane transporter/Ion channel|||Stem Cells

Target: ATPase|||Hedgehog/Smoothened

Receptor: N/A

Bioactivity: Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation and it also inhibits dynein-dependent microtubule gliding and ATPase activity in vitro.

Molecular Weight: 392, 62

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