Product Overview
Ciliobrevin D | T14965 | TargetMol Chemicals
CAS: 1370554-01-0
Smiles: Clc1ccc(C(=O)C(\C#N)=C2/NC(=O)c3ccc(Cl)cc3N2)c(Cl)c1
Formula: C17H8Cl3N3O2
Pathway: GPCR/G Protein|||Membrane transporter/Ion channel|||Stem Cells
Target: ATPase|||Hedgehog/Smoothened
Receptor: N/A
Bioactivity: Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation and it also inhibits dynein-dependent microtubule gliding and ATPase activity in vitro.
Molecular Weight: 392, 62