Product Overview
Cimidahurinine | TN3653 | TargetMol Chemicals
CAS: 142542-89-0
Smiles: OCCc1ccc(O)c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1
Formula: C14H20O8
Pathway: Apoptosis|||Immunology/Inflammation
Target: BCL|||ROS
Receptor: N/A
Bioactivity: Cimidahurinine can attenuate Doxorubicin (DOX)-induced cardiotoxicity in a dose-dependent manner with EC50 values of 45.79 uM; it protects against cardiotoxicity by decreasing reactive oxygen species (ROS) accumulation and downregulating apoptosis-related Bax/Bcl-2 proteins.
Molecular Weight: 316, 3