Product Overview
Cimiside E | TN3655 | TargetMol Chemicals
CAS: 154822-57-8
Smiles: C[C@@H]1C[C@H]2O[C@@]3(O[C@H]2C(C)=C)[C@@H](O)[C@@]2(C)[C@@H]4CC[C@@H]5[C@]6(CC46CC[C@]2(C)C13)CC[C@@H](O[C@@H]1OC[C@@H](O)[C@H](O)[C@H]1O)C5(C)C
Formula: C35H54O8
Pathway: Apoptosis|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||DNA Damage/DNA Repair|||Immunology/Inflammation|||MAPK|||Metabolism|||PI3K/Akt/mTOR signaling
Target: ERK|||TNF|||ROS|||Akt|||PI3K|||PKC|||PPAR
Receptor: N/A
Bioactivity: Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2, PI3K, and PKC are involved in this effect.Cimiside E may be an effective chemopreventive agent against cancer, it arrests cell cycle and induces cell apoptosis in gastric cancer cells.
Molecular Weight: 602, 8
