Product Overview
cjoc42 | T27029 | TargetMol Chemicals
CAS: 2171519-89-2
Smiles: O=C(OC)C1=CC=C(N2N=NC(CCCOS(=O)(C3=CC=C(C)C=C3)=O)=C2)C=C1
Formula: C20H21N3O5S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: cjoc42 is an inhibitor of gankyrin, an ankyrin-repeat oncoprotein whose overexpression has been implicated in the development of many cancer types. cjoc42 prevents the decrease in p53 protein levels normally associated with high amounts of gankyrin, and it restores p53-dependent transcription and sensitivity to DNA damage
Molecular Weight: 415, 46