Coronarin D | TN3708

Coronarin D | TN3708 | TargetMol Chemicals

CAS: 119188-37-3

Smiles: CC1(C)CCC[C@]2(C)[C@@H](C\C=C3/CC(O)OC3=O)C(=C)CC[C@@H]12

Formula: C20H30O3

Pathway: Apoptosis|||Cell Cycle/Checkpoint|||Immunology/Inflammation|||Microbiology/Virology|||Neuroscience|||NF-Κb|||Proteases/Proteasome

Target: BCL|||c-Myc|||TNF|||NF-κB|||Caspase|||COX|||Antifection

Receptor: N/A

Bioactivity: Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) were 2 and 4 mg/mL, respectively; it is active against tested Gram-positive bacteria, inactive for tested Gram-negative bacteria, and weakly active against tested fungi; using coronarin D-antibiotic drug combination can combat the infectious diseases.Coronarin D inhibits NF-kappaB activation pathway, which leads to inhibition of inflammation, invasion, and osteoclastogenesis, as well as potentiation of apoptosis.

Molecular Weight: 318, 5