CRANAD 2 | T22694

CRANAD 2 | T22694 | TargetMol Chemicals

CAS: 1193447-34-5

Smiles: CN(C)c1ccc(\C=C\C(=O)\C=C(/OB(F)F)\C=C\c2ccc(cc2)N(C)C)cc1

Formula: C23H25BF2N2O2

Pathway: Others

Target: Others

Receptor: N/A

Bioactivity: CRANAD-2 is a difluoroboron-derivatized curcumins as near-infrared probe for in vivo detection of amyloid-beta deposits. Upon interacting with Abeta aggregates, CRANAD-2 undergoes a range of changes, which include a 70-fold fluorescence intensity increase, a 90 nm blue shift (from 805 to 715 nm), and a large increase in quantum yield.

Molecular Weight: 410, 27