Product Overview
Crizotinib | T1661 | TargetMol Chemicals
CAS: 877399-52-5
Smiles: C[C@@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl
Formula: C21H22Cl2FN5O
Pathway: Angiogenesis|||Autophagy|||Immunology/Inflammation|||Tyrosine Kinase/Adaptors
Target: c-Met/HGFR|||ROS|||ALK|||Autophagy
Receptor: N/A
Bioactivity: Crizotinib is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.
Molecular Weight: 450, 34
