Product Overview
CU-CPT9b | T7302 | TargetMol Chemicals
CAS: 2162962-69-6
Smiles: Cc1cc(ccc1O)-c1ccnc2cc(O)ccc12
Formula: C16H13NO2
Pathway: Immunology/Inflammation
Target: TLR
Receptor: N/A
Bioactivity: CU-CPT9b is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM). It inhibits activation of NF- B induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.
Molecular Weight: 251, 285
