Product Overview
Cucurbitacin A | TN1533 | TargetMol Chemicals
CAS: 6040-19-3
Smiles: [H][C@@]12C[C@H](O)C(=O)C(C)(C)C1=CC[C@@]1([H])[C@]3(C)C[C@@H](O)[C@H]([C@@](C)(O)C(=O)\C=C\C(C)(C)OC(C)=O)[C@@]3(C)CC(=O)[C@@]21CO
Formula: C32H46O9
Pathway: Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||Stem Cells
Target: ROCK
Receptor: N/A
Bioactivity: Cucurbitacin I, cytotoxic triterpenoid sterols isolated from plants, elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/ROCK pathway and inhibition of LIM-Kinase.
Molecular Weight: 574, 711
