Product Overview
Cyclic ADP-ribose | T19253 | TargetMol Chemicals
CAS: 119340-53-3
Smiles: [H][C@]12COP(O)(=O)OP(O)(=O)OC[C@@]3([H])O[C@]([H])([C@H](O)[C@@H]3O)n3cnc4n(cnc4c3=N)[C@]([H])(O1)[C@H](O)[C@@H]2O
Formula: C15H21N5O13P2
Pathway: Membrane transporter/Ion channel|||Metabolism
Target: Calcium Channel
Receptor: N/A
Bioactivity: Cyclic ADP-ribose (cADPR) is an effective calcium mobilization second messenger, which is synthesized from NAD + by ADP-ribosyl cyclase. Cyclic ADP-ribose mainly increases cytosolic calcium through Ryanodine receptor-mediated endoplasmic reticulum release and extracellular influx caused by the opening of TRPM2 channels.
Molecular Weight: 541, 303
