Product Overview
Decursinol angelate | TN1557 | TargetMol Chemicals
CAS: 130848-06-5
Smiles: C\C=C(\C)C(=O)O[C@H]1Cc2cc3ccc(=O)oc3cc2OC1(C)C
Formula: C19H20O5
Pathway: Angiogenesis|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||MAPK|||Tyrosine Kinase/Adaptors
Target: ERK|||VEGFR|||PKC|||JNK
Receptor: N/A
Bioactivity: Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion and inflammatory activation of cancer cells through modulation of PI3K/AKT, ERK and NF-kappaB, its anti-inflammatory activity may contribute to its anti-cancer activity.
Molecular Weight: 328, 364
