Product Overview
Dehydrodiconiferyl alcohol | TN3802 | TargetMol Chemicals
CAS: 4263-87-0
Smiles: COc1cc(\C=C\CO)cc2C(CO)C(Oc12)c1ccc(O)c(OC)c1
Formula: C20H22O6
Pathway: Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Immunology/Inflammation|||MAPK|||NF-Κb
Target: IL Receptor|||NF-κB|||DNA/RNA Synthesis|||CDK|||JNK
Receptor: N/A
Bioactivity: Dehydrodiconiferyl alcohol shows anti-adipogenic and anti-lipogenic effects in 3T3-L1 cells and primary mouse embryonic fibroblasts. Dehydrodiconiferyl alcohol can modulate the differentiation of Th17 and Th1 cells and suppress experimental autoimmune encephalomyelitis, it may be a potential candidate as an agent for the control of Th17 and Th1-mediated inflammatory diseases. (+)-(2S, 3R)-Dehydrodiconiferyl alcohol is an antioxidant, it has an inhibitory effect on VCAM-1 expression via JNK pathway in endothelial cells and therefore may serve as a novel pharmacological agent to improve endothelial dysfunction.
Molecular Weight: 358, 39
