Product Overview
DNA2 inhibitor C5 | T15146 | TargetMol Chemicals
CAS: 35973-25-2
Smiles: OC(=O)c1cnc2c(cccc2c1O)[N+]([O-])=O
Formula: C10H6N2O5
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM). DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2.
Molecular Weight: 234, 167
