Docetaxel trihydrate | T0186

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Product Overview

Docetaxel trihydrate | T0186 | TargetMol Chemicals

CAS: 148408-66-6

Smiles: O.O.O.CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)c2ccccc2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c3ccccc3)C(C)=C([C@@H](O)C1=O)C2(C)C

Formula: C43H59NO17

Pathway: Apoptosis|||Cytoskeletal Signaling

Target: Apoptosis|||BCL|||Microtubule Associated

Receptor: N/A

Bioactivity: Docetaxel is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currently plays a central role in the therapy of many solid tumor including breast and lung cancer. Therapy with docetaxel has been associated with a low rate of serum enzyme elevations and rarely to instances of acute hepatic necrosis generally due to severe hypersensitivity reactions or sepsis.

Molecular Weight: 861, 935

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