Product Overview
Doramapimod | T6277 | TargetMol Chemicals
CAS: 285983-48-4
Smiles: Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)c2ccccc12)C(C)(C)C
Formula: C31H37N5O3
Pathway: Autophagy|||MAPK
Target: Raf|||p38 MAPK|||Autophagy
Receptor: N/A
Bioactivity: Doramapimod is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.
Molecular Weight: 527, 669
