Product Overview
Dovitinib Dilactic Acid | T6193 | TargetMol Chemicals
CAS: 852433-84-2
Smiles: CC(O)C(O)=O.CC(O)C(O)=O.CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2c(F)cccc2[nH]c1=O
Formula: C27H33FN6O7
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: VEGFR|||FGFR|||FLT|||c-Kit
Receptor: N/A
Bioactivity: Dovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.
Molecular Weight: 572, 594
