Dovitinib lactate hydrate | T6479

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Product Overview

Dovitinib lactate hydrate | T6479 | TargetMol Chemicals

CAS: 915769-50-5

Smiles: O.CC(O)C(O)=O.CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2c(F)cccc2[nH]c1=O

Formula: C24H29FN6O5

Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors

Target: VEGFR|||FGFR|||FLT|||PDGFR|||c-Kit

Receptor: N/A

Bioactivity: Dovitinib (TKI258) Lactate is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.

Molecular Weight: 500, 531

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