Product Overview
(E/Z)-GSK5182 | T7709 | TargetMol Chemicals
CAS: T7709
Smiles: CN(C)CCOC1=CC=C(C=C1)C(=C(CCCO)C1=CC=CC=C1)C1=CC=C(O)C=C1
Formula: C27H31NO3
Pathway: Endocrinology/Hormones|||Immunology/Inflammation
Target: Estrogen/progestogen Receptor|||ROS
Receptor: N/A
Bioactivity: (E/Z)-GSK5182 is a racemic compound of (E)-GSK5182 and (Z)-GSK5182 isomers. GSK5182 is a highly selective and orally active estrogen-related receptor γ (ERRγ) inverse agonist(IC50 of 79 nM), and also induces reactive oxyen species (ROS) generation in hepatocellular carcinoma
Molecular Weight: 417, 54
