Product Overview
EGFR-IN-12 | T5168 | TargetMol Chemicals
CAS: 879127-07-8
Smiles: FC(F)(F)c1cccc(Nc2cc(Nc3cccc(NC(=O)C4CC4)c3)ncn2)c1
Formula: C21H18F3N5O
Pathway: Angiogenesis|||Apoptosis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||EGFR
Receptor: N/A
Bioactivity: EGFR inhibitor is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.
Molecular Weight: 413, 404
