EGFR-IN-12 | T5168

EGFR-IN-12 | T5168 | TargetMol Chemicals

CAS: 879127-07-8

Smiles: FC(F)(F)c1cccc(Nc2cc(Nc3cccc(NC(=O)C4CC4)c3)ncn2)c1

Formula: C21H18F3N5O

Pathway: Angiogenesis|||Apoptosis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Target: Apoptosis|||EGFR

Receptor: N/A

Bioactivity: EGFR inhibitor is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.

Molecular Weight: 413, 404