Product Overview
(-)-Epipodophyllotoxin | TN7041 | TargetMol Chemicals
CAS: 4375-07-9
Smiles: COc1cc([C@@H]([C@H]([C@H](CO2)[C@@H]3O)C2=O)c2c3cc3OCOc3c2)cc(OC)c1OCCOc1cc([C@@H]([C@H]([C@H](CO2)[C@@H]3O)C2=O)c2c3cc3OCOc3c2)cc(OC)c1OC
Formula: C44H42O16
Pathway: Apoptosis
Target: Apoptosis
Receptor: N/A
Bioactivity: (-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells with GI50s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro.
Molecular Weight: 826, 79