Product Overview
Etravirine | T2551 | TargetMol Chemicals
CAS: 269055-15-4
Smiles: Cc1cc(cc(C)c1Oc1nc(Nc2ccc(cc2)C#N)nc(N)c1Br)C#N
Formula: C20H15BrN6O
Pathway: Microbiology/Virology|||Proteases/Proteasome
Target: HIV Protease|||Reverse Transcriptase
Receptor: N/A
Bioactivity: Etravirine is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that confer resistance to the two most commonly prescribed first-generation NNRTIs. It can bind the enzyme reverse transcriptase (RT) in multiple conformations, both for native and mutant RT, thereby blocking the enzymatic activity of RT.
Molecular Weight: 435, 285