Product Overview
Filanesib TFA | T25418 | TargetMol Chemicals
CAS: 1781834-99-8
Smiles: OC(=O)C(F)(F)F.CON(C)C(=O)N1N=C(S[C@@]1(CCCN)c1ccccc1)c1cc(F)ccc1F
Formula: C22H23F5N4O4S
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Filanesib (ARRY-520) targets the kinesin spindle protein (KSP) with potential antineoplastic activity. ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during the mitotic phase, and consequently cell death in tumor cells that are actively dividing.
Molecular Weight: 534, 5
