Product Overview
Finerenone | T21395 | TargetMol Chemicals
CAS: 1050477-31-0
Smiles: CCOc1ncc(C)c2NC(C)=C([C@@H](c3ccc(cc3OC)C#N)c12)C(N)=O
Formula: C21H22N4O3
Pathway: Endocrinology/Hormones
Target: Glucocorticoid Receptor
Receptor: N/A
Bioactivity: Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold).
Molecular Weight: 378, 432