Product Overview
Flavoglaucin | TN4064 | TargetMol Chemicals
CAS: 523-73-9
Smiles: CCCCCCCc1c(O)cc(CC=C(C)C)c(O)c1C=O
Formula: C19H28O3
Pathway: Apoptosis|||Autophagy|||GPCR/G Protein|||Immunology/Inflammation|||Metabolism|||Neuroscience|||NF-Κb
Target: Phosphatase|||IL Receptor|||TNF|||NOS|||NF-κB|||COX|||Nrf2|||Prostaglandin Receptor|||Autophagy
Receptor: N/A
Bioactivity: Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannabinoid receptors. Flavoglaucin appears to be an antitumor promoter, it also has anti-inflammatory effects, it shows inhibitory effects on inflammatory mediators via the induction of heme oxygenase-1 in lipopolysaccharide-stimulated RAW264.7 macrophages. Flavoglaucin exhibits a significant radical scavenging activity against 1, 1-diphenyl-2-picrylhydrazyl (DPPH) with theIC(50) value of 11.3 microM.
Molecular Weight: 304, 43