Product Overview
Flavopiridol hydrochloride | T2615 | TargetMol Chemicals
CAS: 131740-09-5
Smiles: Cl.CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl
Formula: C21H21Cl2NO5
Pathway: Autophagy|||Cell Cycle/Checkpoint|||Microbiology/Virology|||Proteases/Proteasome
Target: HIV Protease|||CDK|||Autophagy
Receptor: N/A
Bioactivity: Alvocidib Hydrochloride is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. This agent is also a competitive inhibitor of adenosine triphosphate activity.
Molecular Weight: 438, 3
