Product Overview
Ganoderic acid DM | TN1663 | TargetMol Chemicals
CAS: 173075-45-1
Smiles: [H][C@@]12CC(=O)C3=C(CC[C@]4(C)[C@H](CC[C@@]34C)[C@H](C)CC\C=C(/C)C(O)=O)[C@@]1(C)CCC(=O)C2(C)C
Formula: C30H44O4
Pathway: Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Endocrinology/Hormones
Target: PARP|||Androgen Receptor|||CDK
Receptor: N/A
Bioactivity: Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1), this suppression leads to the inhibition of dendritic cell-specific transmembrane protein (DC-STAMP) expression and reduces osteoclast fusion.
Molecular Weight: 468, 678
