Product Overview
Ganoderiol F | TMA1012 | TargetMol Chemicals
CAS: 114567-47-4
Smiles: C[C@H](CCC=C(CO)CO)C1CC[C@@]2(C)C3=CC[C@H]4C(C)(C)C(=O)CC[C@]4(C)C3=CC[C@]12C
Formula: C30H46O3
Pathway: Autophagy|||Endocrinology/Hormones|||Microbiology/Virology|||Proteases/Proteasome
Target: Androgen Receptor|||HIV Protease|||Autophagy
Receptor: N/A
Bioactivity: Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency virus-1 protease with IC(50) values of 20-40 microM. It induced HO-1 expression, activation of the mitogen-activated protein kinase EKR and up-regulation of cyclin-dependent kinase inhibitor p16 and suppressed lipopolysaccharide (LPS)-induced nitric oxide (NO) production.
Molecular Weight: 454, 7
