Product Overview
Garcinone D | TN1674 | TargetMol Chemicals
CAS: 107390-08-9
Smiles: COc1c(O)cc2oc3cc(O)c(CC=C(C)C)c(O)c3c(=O)c2c1CCC(C)(C)O
Formula: C24H28O7
Pathway: Immunology/Inflammation|||JAK/STAT signaling|||Metabolism|||NF-Κb|||Others|||Stem Cells
Target: Others|||Reactive Oxygen Species|||STAT
Receptor: N/A
Bioactivity: Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 activation with IC50 values of 3.2 microM.
Molecular Weight: 428, 481
