Product Overview
GDC-0339 | T15376 | TargetMol Chemicals
CAS: 1428569-85-0
Smiles: Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1N1CC[C@@H](N)[C@H](F)CC1
Formula: C20H22F3N7OS
Pathway: Chromatin/Epigenetic|||JAK/STAT signaling
Target: Pim
Receptor: N/A
Bioactivity: GDC-0339 is discovered as a potential treatment of multiple myeloma. GDC-0339 is an orally bioavailable and well-tolerated inhibitor of the pan-Pim kinase (Kis: 0.03 nM, 0.1 nM, and 0.02 nM for Pim1, Pim2, and Pim3, respectively).
Molecular Weight: 465, 5
