Product Overview
GSK-690693 | T6285 | TargetMol Chemicals
CAS: 937174-76-0
Smiles: CCn1c(nc2c1c(OC[C@H]1CCCNC1)cnc2C#CC(C)(C)O)c1nonc1N
Formula: C21H27N7O3
Pathway: Autophagy|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling|||Proteases/Proteasome
Target: Serine Protease|||Akt|||PKC|||AMPK|||Autophagy
Receptor: N/A
Bioactivity: GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.
Molecular Weight: 425, 48
