Product Overview
GSK620 | T9020 | TargetMol Chemicals
CAS: 2088410-46-0
Smiles: CNC(=O)c1cc(cn(Cc2ccccc2)c1=O)C(=O)NC1CC1
Formula: C18H19N3O3
Pathway: Chromatin/Epigenetic
Target: Epigenetic Reader Domain
Receptor: N/A
Bioactivity: GSK620 is a pan-BD2 inhibitor, which shows an anti-inflammatory phenotype in human whole blood with excellent broad selectivity, developability, and in vivo oral pharmacokinetics.GSK620 is highly selective for the BET-BD2 family of proteins, with >200-fold selectivity over all other bromodomains. GSK620 shows an anti-inflammatory phenotype in human whole blood.
Molecular Weight: 325, 368