Product Overview
ICCB-19 hydrochloride | T8931L | TargetMol Chemicals
CAS: 1803605-68-6
Smiles: Cl.O=C(CSC1=NCCN1)NC1CCCCCC1
Formula: C12H22ClN3OS
Pathway: Apoptosis|||Autophagy|||NF-Κb|||Others
Target: Apoptosis|||Others|||Autophagy|||RIP kinase
Receptor: N/A
Bioactivity: ICCB-19 HCl is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal domain (TRADD-C) and TRAF2 to modulate the ubiquitination of RIPK1 and beclin 1.
Molecular Weight: 291, 84
