Product Overview
IHR-1 | T24159 | TargetMol Chemicals
CAS: 548779-60-8
Smiles: C1=CC(=CC=C1NC(=O)C2=C(C=CC(=C2)Cl)Cl)NC(=O)C3=C(C=CC(=C3)Cl)Cl
Formula: C20H12Cl4N2O2
Pathway: Stem Cells
Target: Smo
Receptor: N/A
Bioactivity: IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.
Molecular Weight: 454, 12
