Product Overview
INCB3344 | TQ0103 | TargetMol Chemicals
CAS: 1262238-11-8
Smiles: CCOC1CN(CC1NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)C1CCC(O)(CC1)c1ccc2OCOc2c1
Formula: C29H34F3N3O6
Pathway: Immunology/Inflammation|||Microbiology/Virology
Target: CCR
Receptor: N/A
Bioactivity: INCB3344 is an effective, specific and orally bioavailable CCR2 antagonist with IC50 values of 9.5 nM (mCCR2) and 5.1 nM (hCCR2) in binding antagonism and 7.8 nM (mCCR2) and in 3.8 nM (hCCR2) antagonism of chemotaxis activity.
Molecular Weight: 577, 601
